Monday, 2 January 2017

Pathogenesis of Orderly Loss of Nerve Fibers in Glaucoma

Chronic Glaucoma, commonly known as glaucoma, is a misunderstood disease since given a separate entity in the 1850s. 

Currently, there are many conflicting views of glaucoma but on one issue we have complete agreement: the million or so densely packed nerve fibers in the optic nerve head are being destroyed in an orderly tandem fashion from peripheral to central, never randomly–a pathogenomonic feature. The orderly destruction of NFs is perhaps the only lead we have in solving the mystery of glaucoma, but rarely discussed. If the NFs were not destroyed in a predictable orderly sequence, the role of perimetry in glaucoma would be meaningless.

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