Age-related macular degeneration
(AMD) is the leading cause of blindness in the elderly individuals in developed
countries. The etiology and pathophysiology of AMD are not fully understood.
Formation of drusen is the main pathological change in AMD. Lipids make up about 40% of drusen volume, thus possible relation between AMD and genes
controlling lipid metabolism could provide novel insights into AMD. Our purpose
was to determine the genotype frequencies of LIPC rs10468017, rs493258 and LPL
rs126789919 in patients with AMD in Lithuanian population.
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