Retinoblastoma in children and uveal melanoma in adults represent two of the most common primary intraocular tumors. The incidence of orbital lesions in rank order of occurrence include: thyroidal associated ophthalmopathy, vascular lesions, idiopathic inflammatory pseudotumor, and lymphoproliferative neoplasia. Patients demonstrating a concomitant intraocular and orbital space occupied lesion are relatively rare and, to the best of our knowledge, this is the first report stressing the underlying causes of concomitant intraocular and intraorbital lesions in the literature. In this paper, we present eight cases showing simultaneous intraocular and orbital soft tissue masses and highlight their clinical, pathological and imaging features.
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