To report a case of refractive neurotrophic corneal ulcer, treated successfully with 20% autologous serum eye drops. A 20 year old male presented with redness and foreign body sensation since three months associated with photophobia and progressive diminution of vision of both the eyes, right eye more than left, since 2 months. At presentation, the best corrected visual acuity in the right eye was 1/60 and left 6/12.
