Prevention of Recurrence of Ligneous Conjunctivitis with Subconjunctival

Ligneous conjunctivitis (LC) is a rare and chronic disorder which is characterized by hard wood-like membranes on palpebral and bulbar conjunctiva. It usually presents when plasminogenfunctional activity is under normal range (80-120%), usually below 52%, andplasminogen level in blood generally <1.2 mg/dl (normal range 6-25 mg/dl). Severity is associated with a low plasminogen functional activity, values below 5% can affect all mucous surfaces, and the disease could present as a systemic disorder. 

LC may occur after infectious conjunctivitis or ophthalmic surgical treatment, associated with recurrence of membranes after removal. Plasminogen topical administration has demonstrated a plausible efficient treatment for preventing the recurrence of LC. The goal of our study is to report the case ofa 6 year-old male child with post infectious LC, that when he was 2 years old presented recurrence of the disease after surgical resection and combined treatment with topical tobramycin, dexamethasone and cyclosporine A. Treatment with autologous fresh frozen plasma (AFFP) resulted in remission of the membranes.