A
34 year old women suffering from rheumatoid arthritis since 20 years had a
complaint of blurred vision in right as she had a problem of corneal
melting. It has been stabilised bytreatment followed by regular monitoring that arthritis was in-active on etanercept.But right cornea revealed 3mm descemetocle, later tectonic corneal
transplantation was done and was prescribed tacrolimus. The histological
examinations done after three years was characterised by complete loss of
corneal stroma due to rheumatoid keratolysis. It has been indicated that
metalloproteinase are active in RA are involved in Keratolysis.
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