Purpose: We reported a rare case of
bilateral chronic central serous chorioretinopathy (CSCR) induced by longterm
exogenous testosterone treatment. Method: A case report. Result: A 52-year-oldman with medical history of diabetes mellitus, hypertension, diabetes insipidus
and hypogonadism presented to our ophthalmologic clinic with unstable blurred
vision of right eye for more than 5 years and vision loss of left eye since
childhood injury. Optical coherence tomography (OCT) showed subfoveal fluid in
both of his eyes.
Fluorescein angiography (FA) revealed fluorescein in multiple
leaking points around the arcade area, which appeared hyper fluorescence not
only in early phase but sustained fluorescein pooling till late phase in both
eyes. According to his medical records, he received intramuscular testosterone injection every two weeks as treatment of hypogonadism for more than 10 years.
His serum level of testosterone was higher than normal range. After focal
photocoagulation in his right eye combined with decreasing frequency of
testosterone intramuscular injection, the subfoveal fluid in both of his eyes
totally resolved with vision improvement.
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